Institut de Génétique Moléculaire de Montpellier (IGMM) - UMR5535

• Wodrich H, Henaff D, Jammart B, Segura-Morales C, Seelmeier S, Coux O, Ruzsics Z, Wiethoff C & EJ Kremer. 2010 A capsid encoded PPxY motif facilitates adenovirus entry. PLoS Pathogens 2010 Mar 19;6(3):e1000808. (download .pdf)

• Lau AA, Hopwood JJ, Kremer EJ, Hemsley KM. (2010) SGSH gene transfer in mucopolysaccharidosis type IIIA mice using canine adenovirus vectors. Mol Genet Metab. 100(2):168-75

• Bennasser Y, C Chable-Bessia, R Triboulet, D Gibbings, C Gwizdek, C Dargemont, EJ Kremer, O Voinnet & M. Benkirane. (2011) Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels. Nature Structure & Molecular Biology Mar;18(3):323-7 (download .pdf)

• Perreau M, Welles HC, Harari A, Hall O, Martin R, Maillard M, Dorta G, Bart PA, Kremer EJ, Tartaglia J, Wagner R, Esteban M, Levy Y & G Pantaleo (2011) DNA-C/NYVAC-C Vaccine Regimen Induces HIV-Specific CD4 and CD8 T-Cell responses in Intestinal Mucosa J Virology Oct (in press)

• Salinas S, Schiavo G & EJ Kremer. 2010. A hitchhiker’s guide to the nervous system: the complex journey of viruses and toxins. Nature Reviews Microbiology Sep;8(9):645-55. (download .pdf)

• Bru T, S Salinas & EJ. Kremer, 2010 An update on canine adenovirus type 2 and its vectors. Viruses 2, 2134-2153; doi:10.3390/v2092134 (download pdf)

• Henaff D, S Salinas & EJ. Kremer, 2011 An adenovirus traffic update: from receptor engagement to the nuclear pore. Future Microbiology 2011 Feb;6:179-92.

• Salinas S, Bilsland L, Henaff D, Weston AE, Keriel A, Schiavo G & EJ Kremer (2009). CAR-associated vesicular transport of an adenovirus in motor neuron axons. PLoS Pathogens 2009 May;5(5):e1000442. (download pdf)

• Kremer EJ, (2009) Mutagenesis of hexon "FX" hepatic tropism. Blood 114(5):929-30 (download pdf)

• D. Henaff / E. Seiradake (co-first authors), H. Wodrich, O. Billet, M. Perreau, C. Hippert, F. Mennechet, G. Schoeh, H. Lortat-Jacob, H. Dreja, S. Ibanes, V. Kalatzis, J.P. Wang, R.W. Finberg, S. Cusack & EJ Kremer. (2009) The Cell Adhesion Molecule Car And Sialic Acid On Human Erythrocyte Dictate Adenovirus In Vivo Biodistribution. PLoS Pathogens Jan; 5(1):e1000277. Epub 2009 Jan 2. (download pdf)

• Perreau M., Pantaleo G., Kremer EJ. (2008) Activation of a dendritic cell-T cell axis by ad5 immune complexes create an improved environment for replication of HIV in T Cells. J. Exp Medicine 205: 2717-2725 (download pdf)

• Maurice T., Hippert C., Serratrice N., Dubois G., Jacquet C., Antignac C., Kremer EJ., Kalatzis V. (2008) Cystine accumulation in the CNS results in severe age-related memory deficits. Neurobiology of Aging 2009 Jun;30(6):987-1000. (download pdf)

• Schoehn G., El Bakkouri M., Fabry CC., Estrozi L., Curiel DT., Billet O., Kajava AV., Ruigrok RW., Kremer EJ. (2008) 3D structure of canine adenovirus serotype 2 capsid. J. Virology 82(7) : 3192-3203 (download pdf)

• Hippert C., Dubois G., Morin C., Disson O., Ibanes S., Jacquet C., Schwendener R., Antignac C., Kremer EJ., Kalatzis V. (2008) Gene transfer may be preventive but not curative for lysosomal storage due to a defective transporter. Molecular Therapy . 16(8) : 1372-1381 (download pdf)

• Henaff D., Kremer EJ. (2008) Tropisme in vivo de l’adénovirus - rôle inattendu de l’héxon. Medicine & Science Aug-Sep;24(8-9):673-5 (download pdf)

• Perreau M., Guerin MC., Drouet C. & Kremer EJ. (2007) Interaction of human plasma components wiyh a xenogenic adenovirus : implications during gene transfer; Molecular Therapy Nov;15(11):1998-2007 (download pdf)

• Kalatzis V., Serratrice N., Hippert C., Payet O., Arndt C., Cazevieille C., Maurice T., Hamel C., Malecaze F., Antignac C., Müller A. & Kremer EJ. (2007) A temporospatial guide to the ocular anomalies in a cystinosis mouse model. Pediatric Res. Aug;62(2):156-62 (download pdf)

• Perreau M., Mennechet F., SerratriceN., Wodrich H. & Kremer EJ. (2007) Contrasting effects on the phenotypical and functional maturation of human dendritic cells by human, canine and hybrid Ad vectors: implication for clinical efficacy. J. Virology 81(7):3272-84) (download pdf)

• Hnasko TS., Perez FA., ScourasA., LuquetS., Phillips PE., Kremer EJ. & Palmiter RD. (2006) Cre-mediated restoration of dopamine to the dorsal striatum of a dopamine-deficient mouse results in hyperphagia and hyperactivity. Proc Nat Acad Sci U S A . 2006;103: 8858-63 (download pdf)

• Keriel A., René C., Galer C., Zabner J. & Kremer EJ. (2006) Canine adenovirus vectors for lung-directed gene transfer: efficacy, immunity, and duration of transgene expression using helper-dependent vectors. J Virology . 1487-1496 (download pdf)

• Kremer EJ (2005) Gene Transfer to the Central Nervous System: Current state of the art of the viral vectors. Current Genomics 6(1) 13-37 (download review)