{"id":6169,"date":"2021-09-17T15:11:36","date_gmt":"2021-09-17T13:11:36","guid":{"rendered":"https:\/\/www.igmm.cnrs.fr\/first-3d-images-of-a-giant-molecule\/"},"modified":"2021-09-17T15:39:02","modified_gmt":"2021-09-17T13:39:02","slug":"first-3d-images-of-a-giant-molecule","status":"publish","type":"post","link":"https:\/\/www.igmm.cnrs.fr\/en\/first-3d-images-of-a-giant-molecule\/","title":{"rendered":"First 3D images of a giant molecule"},"content":{"rendered":"<p style=\"text-align: justify;\"><span class=\"\">Capturing the structure of large molecular complexes with variable shape is an extremely difficult task. <\/span><\/p>\n<p class=\"smaller\" style=\"text-align: justify;\"><span class=\"\">The work group around Prof. Utz Fischer, University Julius-Maximilian of W\u00fcrzburg (JMU) and\u00a0 Dr R\u00e9my Bordonn\u00e9 (IGMM) now have been able to do it. Thanks to a new approach, they have succeeded in presenting the first three-dimensional model of the entire SMN complex.<\/span><\/p>\n<figure id=\"attachment_6162\" aria-describedby=\"caption-attachment-6162\" style=\"width: 700px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-6162 size-full\" src=\"https:\/\/www.igmm.cnrs.fr\/wp-content\/uploads\/2021\/09\/new-3d-laser-.jpg\" alt=\"\" width=\"700\" height=\"425\" srcset=\"https:\/\/www.igmm.cnrs.fr\/wp-content\/uploads\/2021\/09\/new-3d-laser-.jpg 700w, https:\/\/www.igmm.cnrs.fr\/wp-content\/uploads\/2021\/09\/new-3d-laser--450x273.jpg 450w\" sizes=\"auto, (max-width: 700px) 100vw, 700px\" \/><figcaption id=\"caption-attachment-6162\" class=\"wp-caption-text\">Model of the SMN complex, stained yeast cells can be seen in the background. (Image: Jyotishman Veepaschit \/ AG Fischer)<\/figcaption><\/figure>\n<p><strong>Read more:<\/strong><\/p>\n<p class=\"heading-title\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8287938\/\" target=\"_blank\" rel=\"noopener\">Identification and structural analysis of the Schizosaccharomyces pombe SMN complex<\/a><\/p>\n<p class=\"heading-title\"><span class=\"authors-list-item \" style=\"letter-spacing: 0px;\">Jyotishman Veepaschit<sup class=\"affiliation-links\"> \u00a0<\/sup><span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \" style=\"letter-spacing: 0px;\">Aravindan Viswanathan <span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \" style=\"letter-spacing: 0px;\">R\u00e9my Bordonn\u00e9<sup class=\"affiliation-links\"><span class=\"author-sup-separator\">\u00a0<\/span><\/sup><span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \" style=\"letter-spacing: 0px;\">Clemens Grimm<span class=\"comma\">,\u00a0<\/span><\/span><span class=\"authors-list-item \" style=\"letter-spacing: 0px;\">Utz Fischer<\/span><\/p>\n<div class=\"article-source\"><a href=\"https:\/\/www.igmm.cnrs.fr\/wp-content\/uploads\/2021\/09\/gkab158.pdf\" target=\"_blank\" rel=\"noopener\"><span class=\"cit\">Nucleic Acids Res. 2021 Jul 21;49(13):7207-7223.<\/span><span class=\"citation-doi\"> doi: 10.1093\/nar\/gkab158<\/span><\/a><\/div>\n<div class=\"inline-authors\">\n<div class=\"authors\">\n<div class=\"article-citation\">\n<h6 class=\"journal-actions dropdown-block\" style=\"text-align: center;\"><\/h6>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Capturing the structure of large molecular complexes with variable shape is an extremely difficult task&#8230;<\/p>\n","protected":false},"author":4,"featured_media":6162,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,16],"tags":[],"class_list":["post-6169","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general-news","category-science-en"],"_links":{"self":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts\/6169","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/comments?post=6169"}],"version-history":[{"count":3,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts\/6169\/revisions"}],"predecessor-version":[{"id":6173,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts\/6169\/revisions\/6173"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/media\/6162"}],"wp:attachment":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/media?parent=6169"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/categories?post=6169"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/tags?post=6169"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}