{"id":7073,"date":"2022-04-19T12:05:36","date_gmt":"2022-04-19T10:05:36","guid":{"rendered":"https:\/\/www.igmm.cnrs.fr\/les-mnemons-quand-la-memoire-passe-par-les-proteines-prions\/"},"modified":"2022-04-19T12:43:31","modified_gmt":"2022-04-19T10:43:31","slug":"les-mnemons-quand-la-memoire-passe-par-les-proteines-prions","status":"publish","type":"post","link":"https:\/\/www.igmm.cnrs.fr\/en\/les-mnemons-quand-la-memoire-passe-par-les-proteines-prions\/","title":{"rendered":"Les mnemons : quand la m\u00e9moire passe par les prot\u00e9ines prions"},"content":{"rendered":"<p><a href=\"https:\/\/theconversation.com\/les-mnemons-quand-la-memoire-passe-par-les-proteines-prions-175750\" target=\"_blank\" rel=\"noopener\">Les cellules ont de la m\u00e9moire\u2026 qui pourrait reposer sur des prot\u00e9ines particuli\u00e8res : les \u00ab mnemons \u00bb. Ce m\u00e9canisme, identifi\u00e9 chez la levure, pourrait expliquer des maladies neurod\u00e9g\u00e9n\u00e9ratives.<\/a><\/p>\n<p><a href=\"https:\/\/www.insb.cnrs.fr\/fr\/news-list-filtered?field_topic_type_tid=74\" target=\"_blank\" rel=\"noopener noreferrer\">A voir aussi sur les actualit\u00e9s de l\u2019INSB<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-6512 aligncenter\" style=\"font-weight: bold; background-color: transparent; text-align: inherit; font-size: 16px; letter-spacing: 0px;\" src=\"https:\/\/www.igmm.cnrs.fr\/wp-content\/uploads\/2017\/08\/escape-wt-2.gif\" alt=\"\" width=\"350\" height=\"253\" \/><\/p>\n<div class=\"caption-style\">\n<p style=\"text-align: justify;\"><span style=\"text-align: justify; color: #4f6166; font-size: 14px; letter-spacing: 0px;\">Figure 1. Cellule de levure expos\u00e9e \u00e0 la ph\u00e9romone sexuelle (7nM). La cellule m\u00e8re produit un shmoo puis, au bout d\u2019un moment, reprend son cycle cellulaire pour produire des cellules filles. Celles-ci r\u00e9pondent \u00e0 la ph\u00e9romone. Temps en heures et minutes.<\/span><\/p>\n<\/div>\n<p><a href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(22)00013-6\" target=\"_blank\" rel=\"noopener\">Yasmin Lau, Henry Patrick Oamen, Marcel Grogg, Iuliia Parfenova , Juha Saarikangas, Robin Hannay, Richard Alan Nichols , Donald Hilvert , Yves Barral, <strong>Fabrice Caudron.<\/strong> Whi3 mnemon association with endoplasmic reticulum membranes confines the memory of deceptive courtship to the yeast mother cell.<\/a> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35085498\/\" target=\"_blank\" rel=\"noopener\"><strong>Curr Biol.<\/strong> 2022 Mar 14;32(5):963-974.e7. doi: 10.1016\/j.cub.2022.01.002. Epub 2022 Jan 31.<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Les cellules ont de la m\u00e9moire\u2026 qui pourrait reposer sur des prot\u00e9ines particuli\u00e8res : les \u00ab mnemons \u00bb. Ce m\u00e9canisme, identifi\u00e9 chez la levure, pourrait expliquer des maladies neurod\u00e9g\u00e9n\u00e9ratives.<\/p>\n","protected":false},"author":4,"featured_media":6511,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,16],"tags":[],"class_list":["post-7073","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general-news","category-science-en"],"_links":{"self":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts\/7073","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/comments?post=7073"}],"version-history":[{"count":2,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts\/7073\/revisions"}],"predecessor-version":[{"id":7077,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts\/7073\/revisions\/7077"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/media\/6511"}],"wp:attachment":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/media?parent=7073"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/categories?post=7073"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/tags?post=7073"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}