{"id":9860,"date":"2026-09-21T13:25:32","date_gmt":"2026-09-21T11:25:32","guid":{"rendered":"https:\/\/www.igmm.cnrs.fr\/sting-from-immunity-to-metabolism\/"},"modified":"2026-09-22T10:45:41","modified_gmt":"2026-09-22T08:45:41","slug":"sting-from-immunity-to-metabolism","status":"publish","type":"post","link":"https:\/\/www.igmm.cnrs.fr\/en\/sting-from-immunity-to-metabolism\/","title":{"rendered":"STING: From Immunity to Metabolism"},"content":{"rendered":"

\"\"<\/p>\n

A recent publication from Nadine Laguette\u2019s team, featured in Nature Communications<\/em><\/a>, reveals an ancestral role of the STING protein in the regulation of lipid metabolism.<\/p>\n

The researchers demonstrate that STING regulates lipid metabolism through FADS2, uncovering a previously unknown function that predates its well-established role in innate immunity.<\/p>\n

These findings provide new insights into the evolutionary history of STING and highlight the close interplay between metabolism and immunity.<\/p>\n

Reference:<\/strong><\/p>\n

Guha, S., Re, J., Gr\u00e9goire, S. et al.<\/em> Evolutionary conservation analysis reveals a primordial function of STING as a regulator of lipid metabolism via FADS2. Nat Commun<\/em> 17<\/strong>, 9771 (2026). https:\/\/doi.org\/10.1038\/s41467-026-76833-5<\/a><\/p>\n

More information is available on the CNRS Biology website.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

A recent publication from Nadine Laguette\u2019s team, featured in Nature Communications, reveals an ancestral role of the STING protein in the regulation of lipid metabolism.<\/p>\n","protected":false},"author":4,"featured_media":9858,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-9860","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general-news"],"_links":{"self":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts\/9860","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/comments?post=9860"}],"version-history":[{"count":4,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts\/9860\/revisions"}],"predecessor-version":[{"id":9866,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/posts\/9860\/revisions\/9866"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/media\/9858"}],"wp:attachment":[{"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/media?parent=9860"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/categories?post=9860"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.igmm.cnrs.fr\/en\/wp-json\/wp\/v2\/tags?post=9860"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}