The Montpellier Institute of Molecular Genetics is recruiting new group leaders to strengthen its research in cancer biology. All proposals with potential synergies to research themes at IGMM will be considered. Particular attention will be paid to projects addressing the early events of tumorigenesis, relationships with the micro-environment and tumor immunology.
|Sir Paul NURSE, Friday, May 22nd, 2015 at 10:00 AM, Amphithéâtre DR-LR, "Understanding Cell Cycle Control"|
|Hepatitis C viral (HCV) infection provokes a major remodeling of hepatocyte physiology. One early manifestation of chronic hepatitis C is deregulation of lipid metabolism and the ensuing accumulation of fat droplets in hepatocytes (liver steatosis). This human pathology is reproduced in transgenic mice with liver-targeted expression of physiological levels of the full complement of viral proteins. A recent publication from the group "HCV and Cancer" (Moreau et al. 2015. Hepatitis C viral (...)|
|Genomic imprinting is an epigenetic phenomenon which mediates parent-of-origin specific, mono-allelic gene expression. In a study published in Developmental Cell, the laboratory of Robert Feil explored how imprinted gene expression is regulated at the developmentally-important Dlk1-Dio3 domain. Studying stem cells, they discovered that this process is linked to maternal expression of non-coding RNAs (ncRNAs) from the domain’s ‘Imprinting Control Region’ (ICR). Disruption of the ICR ncRNA (...)|
|Acute Myleoid Leukemia (AML) are the most frequent leukemia in adults. Their treatment consist of a so-called induction therapy made up of two genotoxic agents: cytarabine (Ara-C) and an antracyclin (daunorubicin or idarubicin). Induction chemotherapy is then followed by a so-called consolidation treatment based on Ara-C only. AML treatments have unfortunately poorly been improved these past 30 years, the problem being agravated by the fact that these leukemia consistute an heterogeneous (...)|
Two types of seminars are organized on a regular basis at IGMM: (i) weekly internal seminar (...)
IGMM has a long-standing tradition of training by and for research. Thus, all groups are used (...)