is a multidisciplinary institute for advanced studies in biology. It has an internationally-acknowledged reputation in the fields of genetic and epigenetic regulations, RNA biology as well as cell cycle, death and metabolism. Its work also has impact in biomedical research on cancer, infectious illnesses and genetic diseases via the development of novel biotherapies and diagnostic tools as well as the launching of biotech start-up companies.

The cell cycle is driven by cyclin-dependent kinases (CDKs). How the global changes in protein phosphorylation mediated by CDKs promote a rapid and ordered cell reorganisation at mitosis onset has long been a mystery…

Dravet syndrome (DS), or severe myoclonic epilepsy of infancy, is a rare form of epilepsy affecting …

Histone post-translational modifications control several fundamental processes on DNA, but very few phosphorylations are known. Here, Fisher, Krasinska and colleagues describe a new phosphorylation…

Guillaume Bossis’ team showed in this manuscript published in Nucleic Acids Research that daunorubicin, the main chemotherapeutic drug used for Acute Myeloid Leukemias, a severe blood cancer…

Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions.
Deleuze V, Garcia L, Rouaisnel B, Salma M, Kinoo A, Andrieu-Soler C, Soler E.
iScience. 2023 Aug 15;26(9):107641. doi: 10.1016/j.isci.2023.107641. eCollection 2023 Sep 15.