Zoe DENIS (PhD Student)
In LAB :
Identify and characterize host factors involved in:
- The restriction of Deltaviruses (ISGs) through an ISG screening
- The replication and the persistence of Deltaviruses through a genome-wide CRISPR-Cas9 screen
Outside LAB :
Likes Climbing (serious climber) and traveling
Pierre KHALFI (Post-Doc)
In LAB :
- Setting up tools and readouts to study the replication of deltaviruses (e.g.stable deltaviruses expressing cell lines, mouse model, smFISH, Northern Blot.)
- Comprehensive identification of deltavirus RNA-binding proteins by mass spectrometry (ChIRP-MS). I am now using these tools to determine which of the host factors I have identified can control
Outside LAB :
Likes Scuba diving, cycling and cocktails
Joe MCKELLAR (Post-Doc)
In LAB :
- Resolving the structure of Deltavirus RNPs in the context of the cell or in viral particles by cryo-EM.
- Developing new techniques to visualize Deltavirus infections in cells.
- Understanding the rules that govern Deltavirus assembly with glycoproteins of helper viruses.
Outside LAB :
I am an amateur home cook and enjoy participating in competitive Magic The Gathering tournaments.
Roni SLEIMAN (PhD Student)
In LAB:
- Resolve Deltavirus particle and RNP structure by Cryo-EM techniques
- Development of new molecular tools to detect , track and visualize Delta RNPs.
Outside LAB:
In his free time, seeks one of two things; Either peace and quiet, or a blast with friends over food and cocktails!
Louison BOIS (Master 2 Intern)
In LAB:
Investigates the replication of circular RNA viruses Deltaviruses and Ambiviruses in the two divergent yeast species, Saccharomyces cerevisiae and Schizosaccharomyces pombe.
Outside LAB :
Enjoys running, climbing and going out with friends
Leila BLAIR (Lab Manager)
In LAB:
- Implement and develop molecular tools for the study of Deltaviruses.
- Ensure efficiency in laboratory manipulations through resource management and the creation and maintenance of organizational systems.
Outside LAB :
When I'm not in the lab I enjoy going for walks in nature spaces, volunteering, cooking/baking, and making art, like watercolor, pastels or collage.
Valérie COURGNAUD (CRHC/ Scientist)
In LAB :
-Focuses on the impact of interactions between viruses and their hosts, mainly on retroviruses, HDVs and delta-like viruses in animals.
I'm interested in viral evolution and cross-species transmission. Using genetic screens, my projects currently focus on identifying genes involved in resistance to viral infection,
with a particular interest in interferon-regulated proteins and on deciphering the mechanisms involved in these processes.
Outside lab :
Reading, swimming, and lot of others things…..