AGENDA

Jeremie Candotti (IGMM)

IGMM & BIOLuM External Seminar
Genome Dynamics & RNA Biology Axis

Senescent cells cluster CTCF on nuclear speckles to instruct their splicing program

https://papantonislab.eu/

CRBM External Seminar

From sequence to function: Insights from Hox Proteins

Contact: albert.tsai@crbm.cnrs.fr

IGMM External Seminar

Title : "Networks of alternative splicing regulation in cancer"
Contact : julie.carnesecchi@igmm.cnrs.fr

"ZEB1, a factor of the epithelial–mesenchymal transition: a novel player in the regulation of erythropoiesis"

Nicolas Ferrary (intern student in Fabrice Caudron's Lab)

CRBM External Seminar
Contact: patrick.lemaire@crbm.cnrs.fr

"A quantitative model of a phenotypically variable structural defect"

The Drosophila larval trachea is a tractable model for quantitatively studying developmental defects and cell fate determination. In the trachea, progenitor cells robustly organize themselves into distinct cell fates, driven by an external morphogen concentrations. Perturbing the external (FGF) signal, we record stochastic phenotypes in which a variable number of "terminal" cells occur. Using live imaging, we observe how fate determination occurs dynamically and quantify morphological trajectories. To quantitatively model stochastic phenotypic outcomes, we turn to a modified "threshold-liability" model from genetics, and use this to predict outcomes in gain-of-function mutants.

Étude des réseaux de régulation basés sur les TF contrôlant la différenciation érythroïde terminale

Contact: dimitris.xirodimas@crbm.cnrs.fr

Contact: dimitris.xirodimas@crbm.cnrs.fr

Contact: dimitris.xirodimas@crbm.cnrs.fr

Contact: dimitris.xirodimas@crbm.cnrs.fr