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The Institute of Molecular Genetics of Montpellier

is a multidisciplinary institute for advanced studies in biology. It has an internationally-acknowledged reputation in the fields of genetic and epigenetic regulations, RNA biology as well as cell cycle, death and metabolism. Its work also has impact in biomedical research on cancer, infectious illnesses and genetic diseases via the development of novel biotherapies and diagnostic tools as well as the launching of biotech start-up companies.

Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs

Pioneer transcription factors can engage nucleosomal DNA, which leads to local chromatin remodeling and to the establishment of transcriptional competence

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Identification of a pathway regulating α-synuclein expression that could be used to develop new therapeutic strategies for Parkinson’s disease.

In this work, published in Cell Reports, Lassot et al. (« Molecular Mechanisms of Apoptosis Regulation»; Solange Desagher) describe a pathway regulating α-synuclein

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HRS-seq : a new genomic method reveals the importance of nuclear bodies in organizing the active chromosomal compartment

In a work published in Genome Research, Marie-Odile Baudement and its colleagues (team « Genome organization and epigenetic control » led by Thierry Forné), have developed the HRS-seq, a new straightforward genome-wide approach whereby they isolated and sequenced genomic regions associated with nuclear bodies…

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Two TRIM proteins control the degradation and the anti-apoptotic activity of BCL2A1 in melanoma cells.

Failure to eliminate cancer cells by apoptosis is crucial in tumor development. Therefore, the key approach to achieving successful antitumor response is to harness stratégies …

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Open Positions: Internships, PhD Thesis, Post-Docs, Technicians, Engineers

IGMM has a long-standing tradition of training by and for research. Thus, all groups are used to host students at different stages of their cursus, including PhD Thesis. They also welcome Post-Docs, Engineers and Technicians.

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  • Joint Seminars Series
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  • Dr Raphaël Margueron (Institut Curie, Paris)
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  • Davide Normanno CRCM - Single-molecule analysis of DNA repair and transport mechanisms
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Upcoming events
  • 29 January 2019  10 h 30 min - 12 h 00 min

    Davide Normanno CRCM - Single-molecule analysis of DNA repair and transport mechanisms

    IGMM seminar room

  • 1 February 2019  11 h 00 min - 12 h 00 min

    Nicolas Manel (Institut Curie)

    Salle Marcel Doree

  • 5 February 2019  10 h 30 min - 12 h 00 min

    Stéphanie Miserey-Lenkei (Institut Curie)

    Marcel Dorée Seminar Room

  • 21 February 2019  11 h 00 min - 12 h 00 min

    Joint Seminar Series

    Amphitheatre DR13

  • 21 March 2019  11 h 00 min - 12 h 00 min

    Joint Seminar Series

    Amphitheatre DR13