Capturing the structure of large molecular complexes with variable shape is an extremely difficult task.
The work group around Prof. Utz Fischer, University Julius-Maximilian of Würzburg (JMU) and Dr Rémy Bordonné (IGMM) now have been able to do it. Thanks to a new approach, they have succeeded in presenting the first three-dimensional model of the entire SMN complex.
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Identification and structural analysis of the Schizosaccharomyces pombe SMN complex
