Human neuromuscular junction on micro-structured microfluidic devices implemented with a custom Micro Electrode Array (MEA) In the neuromuscular system, signal transmission from motor neurons (MNs) to innervated muscle fibers is crucial for…
First 3D images of a giant molecule Capturing the structure of large molecular complexes with variable shape is an extremely difficult task…
The R2TP chaperone activates cell proliferation through the assembly of essential nanomachines The R2TP chaperone recruits HSP90 to assemble numerous cellular nanomachines …
Cellular noise: one mechanism, two models Dans les cellules, la lecture de l’information génétique ne se fait pas continûment, mais de manière …
Ki-67 regulates global gene expression and promotes sequential stages of carcinogenesis Here, we throw light on the roles in cancer of the mysterious cell proliferation antigen Ki-67. Ki-67 …
Lighting up the central dogma in living embryos: imaging transcription and translation and their spatio-temporal dynamics. During development, precise control of gene expression allows ….
Identification of long regulatory elements in eukaryotic genomes Long regulatory elements (LREs), such as CpG islands, polydA:dT tracts or AU-rich elements, are thought to play key roles in gene regulation but …
MAUD BORENSZTEIN LAUREATE OF THE “PRIX CHARLES THIBAULT JUNIOR 2020” The “Prix Charles Thibault Junior 2020” will be given to Maud BORENSZTEIN by the GDR Repro on Tuesday 27 April 2021, during the ReproSciences 2021 conference.
An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism The metabolic changes controlling the stepwise differentiation of human stem and progenitor cells (HSPCs) to mature erythrocytes are poorly understood…
A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport A recent paper by Safieddine et al. in E. Bertrand’s lab published in Nature Communications demonstrates the existence of a conserved family of eight centrosomal mRNAs
