Publications

Lamin C Counteracts Glucose Intolerance in Aging, Obesity and Diabetes Through β-Cell Adaptation

Marion de Toledo, Isabel C. Lopez-Mejia, Patricia Cavelier, Marine Pratlong, Célia Barrachina, Xavier Gromada, Jean-Sébastien Annicotte, Jamal Tazi, Carine Chavey

Diabetes 2020

Immunopathological manifestations in Kabuki syndrome: a registry study of 177 individuals.

Margot H, Boursier G, Duflos C, Sanchez E, Amiel J, Andrau JC, Arpin S, Brischoux-Boucher E, Boute O, Burglen L, Caille C, Capri Y, Collignon P, Conrad S, Cormier-Daire V, Delplancq G, Dieterich K, Dollfus H, Fradin M, Faivre L, Fernandes H, Francannet C, Gatinois V, Gerard M, Goldenberg A, Ghoumid J, Grotto S, Guerrot AM, Guichet A, Isidor B, Jacquemont ML, Julia S, Khau Van Kien P, Legendre M, Le Quan Sang KH, Leheup B, Lyonnet S, Magry V, Manouvrier S, Martin D, Morel G, Munnich A, Naudion S, Odent S, Perrin L, Petit F, Philip N, Rio M, Robbe J, Rossi M, Sarrazin E, Toutain A, Van Gils J, Vera G, Verloes A, Weber S, Whalen S, Sanlaville D, Lacombe D, Aladjidi N, Geneviève D.

Genet Med. 2020 / vol 22(1) / pages 181-188

Hypoxia differently modulates the release of mitochondrial and nuclear DNA

A. Otandault, J. D. Abraham, Z. Al Amir Dache, A. Khalyfa, I. Jariel-Encontre, T. Forné, C. Prévostel, S. Chouaib, D. Gozal and A. R. Thierry

British J. of Cancer 2020 / vol 122 (5) / pages 715-725

Stability and Lability of Parental Methylation Imprints in Development and Disease.

Farhadova S, Gomez-Velazquez M, Feil R.

Genes (Basel) 2019 / vol 10(12) / pages pii: E999

CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains.

Llères D, Moindrot B, Pathak R, Piras V, Matelot M, Pignard B, Marchand A, Poncelet M, Perrin A, Tellier V, Feil R, Noordermeer D.

Genome Biol 2019 / vol 20(1) / pages 272

Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant.

Antoine M, Patrick KL, Soret J, Duc P, Rage F, Cacciottolo R, Nissen KE, Cauchi RJ, Krogan NJ, Guthrie C, Gachet Y, Bordonné R.

iScience 2019 / vol 23(1) / pages 100809

SMN complex member Gemin3 self-interacts and has a functional relationship with ALS-linked proteins TDP-43, FUS and Sod1.

Cacciottolo R, Ciantar J, Lanfranco M, Borg RM, Vassallo N, Bordonné R, Cauchi RJ.

Sci Rep. 2019 / vol 9(1) / pages 18666

Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.

Gehrmann U, Burbage M, Zueva E, Goudot C, Esnault C, Ye M, Carpier JM, Burgdorf N, Hoyler T, Suarez G, Joannas L, Heurtebise-Chrétien S, Durand S, Panes R, Bellemare-Pelletier A, Sáez PJ, Aprahamian F, Lefevre D, Adoue V, Zine El Aabidine A, Muhammad Ahmad M, Hivroz C, Joffre O, Cammas F, Kroemer G, Gagnon E, Andrau JC, Amigorena S

Proc Natl Acad Sci U S A. 2019 / vol 116(51) / pages 25839-25849

Exploring Mammalian Genome within Phase-Separated Nuclear Bodies: Experimental Methods and Implications for Gene Expression.

Lesne A, Baudement MO, Rebouissou C, Forné T.

Genes (Basel) 2019 / vol 10(12) / pages pii: E1049

[Zelda, maestro of the zygotic genome awakening].

Dufourt J, Bellec M, Messina O, Trullo A, Favard C, Radulescu O, Lagha M.

Med Sci (Paris) 2019 / vol 35(11) / pages 821-841

MitoTrack, a user-friendly semi-automatic software for lineage tracking in living embryos.

Trullo A, Dufourt J, Lagha M.

Bioinformatics 2019 / pages pii: btz717

Particulate matter-induced senescence of skin keratinocytes involves oxidative stress-dependent epigenetic modifications.

Ryu YS, Kang KA, Piao MJ, Ahn MJ, Yi JM, Bossis G, Hyun YM, Park CO, Hyun JW.

Exp Mol Med. 2019 / vol 51(9) / pages 108

Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses.

Bauer KE, Segura I, Gaspar I, Scheuss V, Illig C, Ammer G, Hutten S, Basyuk E, Fernández-Moya SM, Ehses J, Bertrand E, Kiebler MA.

Nat Commun 2019 / vol 10(1) / pages 3178

Intrathymic adeno-associated virus gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells.

Pouzolles M, Machado A, Guilbaud M, Irla M, Gailhac S, Barennes P, Cesana D, Calabria A, Benedicenti F, Sergé A, Raman I, Li QZ, Montini E, Klatzmann D, Adjali O, Taylor N*, Zimmermann VS*

J Allergy Clin Immunol 2019 / vol pii: S0091-6749(19) / pages 31171-6

The SUMO Pathway in Hematomalignancies and Their Response to Therapies.

Boulanger M, Paolillo R, Piechaczyk M, Bossis G.

Int J Mol Sci 2019 / vol 20(16) / pages pii: E3895

Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia.

Hosseini M, Rezvani H, Aroua N, Bosc C, Farge T, Saland E, Guyonnet-Dupérat V, Zaghdoudi S, Jarrou L, Larrue C, Sabatier M, Mouchel PL, Gotanègre M, Piechaczyk M, Bossis G, Récher C, Sarry JE.

Cancer Res 2019 / pages pii: canres.0515.2019

Lighting Up Gene Activation in Living Drosophila Embryos.

Fernandez C. , Lagha M.

Methods Mol Biol 2019 / vol 2038 / pages 63-74

Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia.

Hosseini M, Rezvani H, Aroua N, Bosc C, Farge T, Saland E, Guyonnet-Dupérat V, Zaghdoudi S, Jarrou L, Larrue C, Sabatier M, Mouchel PL, Gotanègre M, Piechaczyk M, Bossis G, Récher C, Sarry JE.

Cancer Res. 2019 / vol 79 (20) / pages 5191-5203

Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells

Isabelle Clerc1*, Daouda Abba Moussa1*, Zoi Vahlas1*, Saverio Tardito2,3, Leal  Oburoglu1, Thomas J. Hope4, Marc Sitbon1, Valérie Dardalhon1, Cédric  Mongellaz1#, and Naomi Taylor1#^

Nature Metabolism 2019 / vol 1 / pages 717-730

AP-1 signalling by Fra-1 directly regulates HMGA1 oncogene transcription in Triple Negative Breast Cancers.

Tolza, C., Bejjani, F., Evanno, E., Mahfoud, S., Moquet-Torcy, G., Gostan, T., Maqbool, O., Kirsh, O., Piechaczyk, M. and Jariel-Encontre, I.

Molec. Cancer Res. 2019 / vol 17 (10) / pages 1999-2014

A review of 65 years of human adenovirus seroprevalence

Mennechet, F. J. D. Paris, O. Ouoba, A. R. Salazar Arenas, S. Sirima, S. B. Takoudjou Dzomo, G. R. Diarra, A. Traore, I. T. Kania, D. Eichholz, K. Weaver, E. A. Tuaillon, E. Kremer, E. J.

2019 / pages 1-17

Combination of metformin with sodium selenite induces a functional phenotypic switch of human GM-CSF monocyte-derived macrophages.

Meziane W, Mekkaoui Z, Hai I, Kacimi K, Djilali K, Touil-Boukoffa C, Lefranc G, Fernandez A, Lamb N, Mennechet F, Aribi M.

Int Immunopharmacol. 2019 4 / vol 73 / pages 212-224

The AP-1 transcriptional complex: Local switch or remote command?

Bejjani F., Evanno E., Zibara K., Piechaczyk M., Jariel-Encontre I.

Biochim Biophys Acta Rev Cancer. 2019 / vol 1972 / pages 11-23

Characterization of XPR1/SLC53A1 variants located outside of the SPX domain in patients with primary familial brain calcification.

López-Sánchez U, Nicolas G, Richard AC, Maltête D, Charif M, Ayrignac X, Goizet C, Touhami J, Labesse G, Battini JL, Sitbon M.

Sci Rep. 2019 / vol 9(1) / pages 6776

The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre-insertion Sequence Biases and Post-insertion Selection.

Sultana T, van Essen D, Siol O, Bailly-Bechet M, Philippe C, Zine El Aabidine A, Pioger L, Nigumann P, Saccani S, Andrau JC, Gilbert N, Cristofari G.

Mol Cell. 2019 / vol 74(3) / pages 555-570

Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection.

Au Yeung WK, Brind'Amour J, Hatano Y, Yamagata K, Feil R, Lorincz MC, Tachibana M, Shinkai Y, Sasaki H.

Cell Rep 2019 / vol 27(1) / pages 282-293.e4

Mineralocorticoid Receptor Antagonism Limits Experimental Choroidal Neovascularization and Structural Changes Associated With Neovascular Age-Related Macular Degeneration

Min Zhao 1 2 3 , Irmela Mantel 4 , Emmanuelle Gelize 1 2 3 , Xinxin Li 1 2 3 , Xiaoyue Xie 1 2 3 , Alejandro Arboleda 1 2 3 5 , Marie Seminel 1 2 3 , Rinath Levy-Boukris 1 2 3 , Marilyn Dernigoghossian 1 2 3 , Andrea Prunotto 6 , Charlotte Andrieu-Soler 7 , Carlo Rivolta 6 8 , Jérémie Canonica 4 , Marie-Christine Naud 1 2 3 , Sebastian Lechner 2 3 9 , Nicolette Farman 2 3 9 , Irene Bravo-Osuna 10 11 12 , Rocio Herrero-Vanrell 10 11 12 , Frederic Jaisser 2 3 9 , Francine Behar-Cohen 13 14 15 16

Nat Commun 2019 / vol 10 (1) / pages 369

[Rheumatology, the Multitude of Options]

Jacques Morel 1 , Denis Mulleman 2

Med Sci (Paris) 2019 / vol 35 (12) / pages 1029-1033

[Monoclonal Antibodies in Infectious Diseases: New Partners in the Therapeutic Arsenal]

Guillaume Desoubeaux 1 , Mireia Pelegrin 2

Med Sci (Paris) Dec 2019 / vol 35 (12) / pages 1008-1013

Probing transcription factor combinatorics in different promoter classes and in enhancers.

Vandel J., Cassan O., Lebre S., Lecellier CH*, Brehelin L*.

BMC Genomics 2019 / vol 20(1) / pages 103

Genomic Imprinting and Physiological Processes in Mammals.

Tucci V, Bartolomei MS, Benvenisty N, Bourc'his D, Charalambous M, Dulac C, Erice Imprinting Group : Feil R, Glaser J, Huelsmann L, John RM, McNamara GI, Moorwood K, Muscatelli F, Sasaki H, Strassmann BI, Vincenz C, Wilkins J, Isles AR, Kelsey G, Ferguson-Smith AC.

Cell 2019 / vol 176(5) / pages 952-965

Microscopy-Based Chromosome Conformation Capture Enables Simultaneous Visualization of Genome Organization and Transcription in Intact Organisms.

Cardozo Gizzi AM, Cattoni DI, Fiche JB, Espinola SM, Gurgo J, Messina O, Houbron C, Ogiyama Y, Papadopoulos GL, Cavalli G, Lagha M, Nollmann M.

Mol Cell. 2019 / vol pii: S1097-2765(19)30011-5

Probing transcription factor combinatorics in different promoter classes and in enhancers.

Vandel J, Cassan O, Lèbre S, Lecellier CH*, Bréhélin L*.

BMC Genomics. 2019 / vol 20(1) / pages 103

Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing.

Vautrin A, Manchon L, Garcel A, Campos N, Lapasset L, Laaref AM, Bruno R, Gislard M, Dubois E, Scherrer D, Ehrlich JH, Tazi J.

Sci Rep. 2019 / vol 9(1) / pages 792

Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phase IIa randomised controlled study.

Rutsaert S, Steens JM, Gineste P, Cole B, Kint S, Barrett PN, Tazi J, Scherrer D, Ehrlich HJ, Vandekerckhove L

J Virus Erad. 2019 / vol 5(1) / pages 10-22.

Non-Cell Cycle Functions of the CDK Network in Ciliogenesis: Recycling the Cell Cycle Oscillator

Krasinska L, Fisher D.

Bioessays 2018 / vol 40 / pages e1800016

The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21.

Lassot I, Mora S, Lesage S, Zieba BA, Coque E, Condroyer C, Bossowski JP, Mojsa B, Marelli C, Soulet C, Tesson C, Carballo-Carbajal I, Laguna A, Mangone G, Vila M, Brice A, Desagher S.

Cell Rep 2018 / vol 25(9) / pages 2484-2496

Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs.

Dufourt J, Trullo A, Hunter J, Fernandez C, Lazaro J, Dejean M, Morales L, Nait-Amer S, Schulz KN, Harrison MM, Favard C, Radulescu O, Lagha M.

Nat Commun 2018 / vol 9(1) / pages 5194

Remembering the past: Mitotic bookmarking in a developing embryo.

Bellec M, Radulescu O, Lagha M.

Curr Opin Syst Biol 2018 / vol 11 / pages 41-49

Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence the outcome of mutagenic DNA repair

Kallimasioti-Pazi EM1, Thelakkad Chathoth K1, Taylor GC1, Meynert A1, Ballinger T1, Kelder MJE1, Lalevée S2, Sanli I2, Feil R2, Wood AJ1

PLos Biol 2018 / vol 16(12) / pages e2005595

Archives

Lamin C Counteracts Glucose Intolerance in Aging, Obesity and Diabetes Through β-Cell Adaptation

Immunopathological manifestations in Kabuki syndrome: a registry study of 177 individuals.

Hypoxia differently modulates the release of mitochondrial and nuclear DNA

Stability and Lability of Parental Methylation Imprints in Development and Disease.

CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains.

Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant.

SMN complex member Gemin3 self-interacts and has a functional relationship with ALS-linked proteins TDP-43, FUS and Sod1.

Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation.

Exploring Mammalian Genome within Phase-Separated Nuclear Bodies: Experimental Methods and Implications for Gene Expression.

[Zelda, maestro of the zygotic genome awakening].

MitoTrack, a user-friendly semi-automatic software for lineage tracking in living embryos.

Particulate matter-induced senescence of skin keratinocytes involves oxidative stress-dependent epigenetic modifications.

Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses.

Intrathymic adeno-associated virus gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells.

The SUMO Pathway in Hematomalignancies and Their Response to Therapies.

Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia.

Lighting Up Gene Activation in Living Drosophila Embryos.

Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia.

Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells

AP-1 signalling by Fra-1 directly regulates HMGA1 oncogene transcription in Triple Negative Breast Cancers.

A review of 65 years of human adenovirus seroprevalence

Combination of metformin with sodium selenite induces a functional phenotypic switch of human GM-CSF monocyte-derived macrophages.

The AP-1 transcriptional complex: Local switch or remote command?

Characterization of XPR1/SLC53A1 variants located outside of the SPX domain in patients with primary familial brain calcification.

The Landscape of L1 Retrotransposons in the Human Genome Is Shaped by Pre-insertion Sequence Biases and Post-insertion Selection.

Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection.

Mineralocorticoid Receptor Antagonism Limits Experimental Choroidal Neovascularization and Structural Changes Associated With Neovascular Age-Related Macular Degeneration

[Rheumatology, the Multitude of Options]

[Monoclonal Antibodies in Infectious Diseases: New Partners in the Therapeutic Arsenal]

Probing transcription factor combinatorics in different promoter classes and in enhancers.

Genomic Imprinting and Physiological Processes in Mammals.

Microscopy-Based Chromosome Conformation Capture Enables Simultaneous Visualization of Genome Organization and Transcription in Intact Organisms.

Probing transcription factor combinatorics in different promoter classes and in enhancers.

Both anti-inflammatory and antiviral properties of novel drug candidate ABX464 are mediated by modulation of RNA splicing.

Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phase IIa randomised controlled study.

Non-Cell Cycle Functions of the CDK Network in Ciliogenesis: Recycling the Cell Cycle Oscillator

The E3 Ubiquitin Ligases TRIM17 and TRIM41 Modulate α-Synuclein Expression by Regulating ZSCAN21.

Temporal control of gene expression by the pioneer factor Zelda through transient interactions in hubs.

Remembering the past: Mitotic bookmarking in a developing embryo.

Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence the outcome of mutagenic DNA repair