Spontaneous control of viral replication during primary HIV infection: when is “HIV controller” status established?

Goujard, C.; Chaix, M. L.; Lambotte, O.; Deveau, C.; Sinet, M.; Guergnon, J.; Courgnaud, V.; Rouzioux, C.; Delfraissy, J. F.; Venet, A.; Meyer, L.

Clin Infect Dis

2009-09-15 / vol 49 / pages 982-6


Eight patients in the ANRS PRIMO cohort experienced early spontaneous viral control. Viral control was established a median of 6.2 months after primary human immunodeficiency virus type 1 infection and lasted a median of 4.1 years. Seven of the patients initially had detectable viral replication. For 4 patients, viral control was lost during follow-up.

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1537-6591 (Electronic) 1058-4838 (Linking)


Female; Humans; Male; Adolescent; Adult; Middle Aged; Young Adult; Aged; Disease Progression; *Virus Replication; CD4-CD8 Ratio; Cohort Studies; HIV Infections/*immunology/*virology; HIV-1/*physiology; Remission, Spontaneous; RNA, Viral/*blood; Viral Load

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