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Synthesis and cellular uptake of fluorescently labeled oligodeoxynucleotide prodrugs.

Dell'Aquila, C.; Vives, E.; Imbach, J. L.; Rayner, B.

Nucleosides & Nucleotides

1999 / vol 18 / pages 1683-1684

Abstract

In this paper we described the synthesis on solid support of 5′-fluorescein labeled dodecathymidylates having internucleoside phosphodiester or phosphorothioate linkages temporary masked with enzymolabile S-pivaloyl-2-thioethyl (tBuSATE) groups.

0732-8311

Tags

solid-phase synthesis

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