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Publication Archives

DNA-PK interacts with cyclic dinucleotides and inhibits type I interferon responses

Isabelle K Vila # 1 , Yasmine Messaoud-Nacer # 1 , Clara Taffoni # 1 , Jane Jardine 2 , Roger J Eloiflin 1 , Adeline Augereau 1 , Soumyabrata Guha 1 , Moritz Schussler 1 , Pierre Le Hars 1 , Joe McKellar 1 , Tamara Carvalho 3 , Jeanne Postal 4 5 , Morgane Chemarin 1 , Joanna Re 1 , Florence Guivel-Benhassine 4 5 , Raphaëlle Lopez 3 , Kilian Trillet 2 , Jennifer Barrat 1 , Maximin Serbier 1 , Insaf El Mansouri 1 , Charlotte Luchsinger 6 , George P Chrousos 7 , Françoise Porrot 4 5 , Felipe Diaz-Griffero 6 , Olivier Schwartz 4 , Fabien P Blanchet 3 , Karim Majzoub 1 , Nicolas Bidère 2 , Dimitrios Vlachakis 7 8 9 , Nadine Laguette 1

J Exp Med . 2026 / pages 223(5):e20251796

Comment : STING signalling as a mediator between lipid metabolism and innate immunity

Soumyabrata Guha & Nadine Laguette

Nature Reviews Molecular Cell Biology (2026)

Disrupted temperature-sleep coupling mechanism in a Dravet syndrome mouse model

Saja Fadila 1 2 3 , Georgii Krivoshein 4 , Hala Majadly 2 5 , Anat Mavashov 2 5 , Shahak Ranen 1 2 , Marina Brusel 2 , Iria G Dopeso-Reyes 6 , Bertrand Beucher 6 7 , Eric J Kremer 6 , Else A Tolner 4 8 , Moran Rubinstein 9 10 11

Nat Commun

Motivational control is implemented by a cingulo-prefrontal network

Clémence Gandaux 1 , Jérôme Sallet 1 , Céline Amiez 1 , Delphine Autran-Clavagnier 1 , Valentine Morel-Latour 1 , Clément Goussi-Denjean 1 , Vincent Fontanier 2 , Pierre Misery 1 , Camille Lamy 1 , Frank Lamberton 3 , Marina Lavigne 4 , Eric J Kremer 4 , Charles R E Wilson 1 , Emmanuel Procyk 5

Curr Biol. 2025 / pages 35(22):5618-5625.e4

Modulation of relative aversive and safety learning by D2-expressing neurons of the anterior paraventricular nucleus of the thalamus

Magdalena Miranda 1 , Elsa Karam 1 , Pola Tuduri 1 , Maïwenn Passard 1 , Majda Drahmani 1 , Loic Vaillant 1 , Christina-Anna Vallianatou 1 , Marina Lavigne 2 , Eric J Kremer 2 , Jeanne Ster 1 , Emmanuel Perisse 3 , Stéphanie Trouche 4

Curr Biol . / pages 35(24):6070-6085.e4.

Autism-associated SCN2A deficiency disrupts cortico-striatal circuitry in human brain assembloids

Xiaoling Chen 1 2 3 , Jingliang Zhang 1 2 3 , Jiaxiang Wu 1 2 , Morgan J Robinson 1 2 4 , Harish Kothandaraman 5 , Ye-Eun Yoo 1 2 , Iria M Gonzalez Dopeso-Reyes 6 , Thomas D Buffenoir 6 , Manasi S Halurkar 1 2 , Zaiyang Zhang 1 2 , Muhan Wang 1 2 , Erin N Creager 7 , Yuanrui Zhao 1 2 , Maria I Olivero-Acosta 1 2 , Kyle W Wettschurack 1 2 , Zhefu Que 1 2 , Chongli Yuan 2 4 , Allison J Schaser 2 8 , Nadia A Lanman 5 9 , Jean-Christophe Rochet 1 2 , William C Skarnes 10 , Eric J Kremer 6 11 , Yang Yang 1 2 5 11 12

bioRxiv2025 Jun 2025

Toll-like receptor 4 – a multifunctional virus recognition receptor

Elina Gerber-Tichet 1 , Fabien P Blanchet 2 , Karim Majzoub 1 , Eric J Kremer 3

Trends Microbiol . 2025 Jan / pages 33(1):34-47.

Deltaviruses spread through a viral Trojan Horse

Joe McKellar 1 , Aurélien Fouillen 2 , Sébastien Lyonnais 3 , Marie-Pierre Blanchard 4 , Florian Seigneuret 5 , Antonio Trullo 1 , Zoé Denis 1 , Roni Sleiman 1 , Brandon Le Bon 6 , Laurence Berry 7 , Lorena Kumarasinghe 8 , Jules Bouget 8 , Arinya Apostel 1 , Maria Bacia-Verloop 6 , Sylvain De Rossi 4 , Yasmine Messaoud-Nacer 1 , Sophie Colomb 9 , Solange Desagher 8 , Isabelle K Vila 1 , Nadine Laguette 1 , Sébastien Granier 2 , Hugues de Rocquigny 5 , Raphael Gaudin 8 , Valérie Courgnaud 1 , Irina Gutsche 6 , Jussi Hepojoki 10 , Karim Majzoub 11

Cell 2026

G-quadruplexes are promoter elements controlling nucleosome exclusion and RNA polymerase II pausing.

Cyril Esnault 1, Amal Zine El Aabidine 2, Marie-Cécile Robert 2 3 4, Anne Cucchiarini 5, Talha Magat 2, Alexia Pigeot 2, Soumya Bouchouika 2, Encar Garcia-Oliver 2, Kevin Gawron 2, Eugénia Basyuk 2 6, Magdalena A Karpinska 2 3 4, Alja Kozulic-Pirher 2 3, Yu Luo 5 7, Daniela Verga 7, Raphael Mourad 8, Ovidiu Radulescu 9, Jean-Louis Mergny 5, Edouard Bertrand 2 3 4, Jean-Christophe Andrau 10 11

Nat Genet . 2025 Aug;57(8):1981-1993. doi: 10.1038/s41588-025-02263-6. Epub 2025 Jul 22. 2025 / vol 57(8) / pages 1981-1993.