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Targeting SUMOylation triggers interferon-ß-dependent activation of patient and allogenic Natural Killer cells in preclinical models of Acute Myeloid Leukemia

Rawan Hallal 1 , Marion de Toledo 2 , Denis Tempé 3 , Rayane Berrahouane 1 , Sara Zemiti 1 , Loïs Coënon 4 , Delphine Gitenay 5 , Simon George 1 , Moritz Schüssler 6 , Nadine Laguette 7 , Sarah Bonnet 8 , Ludovic Gabellier 8 , Guillaume Cartron 1 , Mireia Pelegrin 1 , Martin Villalba 9 , Guillaume Bossis 1

Mol Cancer Ther .

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10.1158/1535-7163.MCT-25-0504

PMC7618005

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